A novel “delayed start” protocol with gonadotropin-releasing hormone antagonist improves outcomes in poor responders
نویسندگان
چکیده
منابع مشابه
Early gonadotropin-releasing hormone antagonist start improves follicular synchronization and pregnancy outcome as compared to the conventional antagonist protocol
OBJECTIVE To assess whether an early GnRH antagonist start leads to better follicular synchronization and an improved clinical pregnancy rate (CPR). METHODS A retrospective cohort study. A total of 218 infertile women who underwent IVF between January 2011 and February 2013. The initial cohort (Cohort I) that underwent IVF between January 2011 and March 2012 included a total of 68 attempted I...
متن کاملPregnancy outcome of “delayed start” GnRH antagonist protocol versus GnRH antagonist protocol in poor responders: A clinical trial study
BACKGROUND Management of poor-responding patients is still major challenge in assisted reproductive techniques (ART). Delayed-start GnRH antagonist protocol is recommended to these patients, but little is known in this regards. OBJECTIVE The goal of this study was assessment of delayed-start GnRH antagonist protocol in poor responders, and in vitro fertilization (IVF) outcomes. MATERIALS AN...
متن کاملmicrodose flare-up gonadotropin-releasing hormone (gnrh) agonist versus gnrh antagonist protocols in poor ovarian responders undergoing intracytoplasmic sperm injection
background: microdose flare-up gnrh agonist and gnrh antagonist have become more popular in the management of poor ovarian responders (por) in recent years; however, the optimal protocol for por patients undergoing in vitro fertilization has still been a challenge. methods: in this observational study design, two hundred forty four poor ovarian responders were retrospectively evaluated for thei...
متن کاملDelayed Start Versus Conventional GnRH Antagonist Protocol in Poor Responders Pretreated With Estradiol in Luteal Phase: A Randomized Controlled Trial.
OBJECTIVE To compare the new delayed start protocol against the conventional gonadotropin (Gn)-releasing hormone antagonist protocol in poor responders (PORs). STUDY DESIGN A total of 160 women with poor response to previous in vitro fertilization (IVF) cycle were randomized either to start Gn then Cetrotide 0.25 subcutaneously (sc) added when leading follicle (DF) reach >12 mm or Cetrotide 0...
متن کاملcomparison pregnancy outcomes between minimal stimulation protocol and conventional gnrh antagonist protocols in poor ovarian responders
objective: to compare the pregnancy outcomes achieved by in vitro fertilization (ivf) between minimal stimulation and conventional antagonist protocols in poor ovarian responders (pors). materials and methods: in this randomized controlled trial, 77 pors undergoing ivf were selected and divided into two groups. first group was the minimal stimulation group (n = 42) receiving 100 mg/day clomiphe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2014
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2014.01.050